As a functional medicine practitioner, I see a wide range of health problems that all stem from chronic inflammation. And while acute inflammation is a natural and healthy response to help fight off pathogenic bacteria and infections, long-term chronic inflammation that doesn’t subside when the threat is gone can contribute to everything from autoimmune conditions to cancer.
^ Epps, David (20 February 2018). "Facts about fasting". The Citizen. Retrieved 16 March 2018. In Methodism, fasting is considered one of the “Works of Piety.” The Discipline of the Wesleyan Methodist Church required Methodists to fast on certain days. Historically, Methodist clergy are required to fast on Wednesdays, in remembrance of the betrayal of Christ, and on Fridays, in remembrance of His crucifixion and death.
Some of the best evidence on the impact of fasting on bodyweight and fat comes from a December 2018 systematic review. The researchers looked at randomized controlled trials of intermittent fasting and found that the people who fasted lost about 4 to 8 percent of their original bodyweight, on average. So fasting worked, but, interestingly, it didn’t outperform regular, continuous calorie restriction (“eat less every day” dieting), and it didn’t lead to dramatic weight loss.
In a physiological context, fasting may refer to the metabolic status of a person who has not eaten overnight, or to the metabolic state achieved after complete digestion and absorption of a meal. Several metabolic adjustments occur during fasting. Some diagnostic tests are used to determine a fasting state. For example, a person is assumed to be fasting once 8–12 hours have elapsed since the last meal. Metabolic changes of the fasting state begin after absorption of a meal (typically 3–5 hours after eating).